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CD11b 抗体

This anti-CD11b antibody is a 大鼠 单克隆 antibody detecting CD11b in FACS, IP, IHC (fro), Func 和 IHC (p). Suitable for 人, 小鼠 和 兔.
产品编号 ABIN319553
发货至: 中国

Quick Overview for CD11b 抗体 (ABIN319553)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

M1-70-15
  • 交叉反应 (详细)

    Species reactivity (expected):Human, Rabbit.
    Species reactivity (tested):Mouse.

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    内毒素水平

    Low Endotoxin

    免疫原

    T cell enriched splenocytes from B10 mice. Spleen cells from immunised DA rats were fused with cells of the NS1/1.Ag4.1 mouse myeloma cell line.

    亚型

    IgG2b
  • 应用备注

    Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections. Immunoprecipitation. Flow Cytometry: 1/50 - 1/100 (routinely tested in flow cytometry on mouse peritoneal macrophages). Functional Assays: Clone M1/70.15 has been reported to block iC3b binding to its receptor.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level < 0.01EU/ug

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b

    背景

    The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

    基因ID

    10090

    UniProt

    P05555

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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